{"result":[{"lastName":"Miklos","clinicalFocus":[{"focus":"Aplastic Anemia"},{"focus":"Blood Stem Cell Transplant "},{"focus":"Blood and Marrow Transplantation"},{"focus":"Burkitt's Lymphoma"},{"focus":"Cancer - Genetics"},{"focus":"Cutaneous Lymphoma "},{"focus":"Genetics"},{"focus":"Hematology"},{"focus":"Hodgkin's Disease"},{"focus":"Hodgkin's Disease - Blood and Marrow Transplant"},{"focus":"Leukemia"},{"focus":"Leukemia - Blood and Marrow Transplant"},{"focus":"Lymphoma "},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Blood and Marrow Transplant"},{"focus":"Non-Hodgkin's Lymphoma"},{"focus":"Non-Hodgkin's Lymphoma - Blood and Marrow Transplant"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Blood & Marrow Transplantation"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Blood & Marrow Transplantation","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=6165&type=small&showNoImage","displayName":"David Miklos","firstName":"David","href":"http://iti.stanford.edu/profiles/David_Miklos","researchInterest":"Investigates the targets of immune responses after human allogeneic stem cell transplantation. BMT patients develop antibodies against minor histocompatibility antigens (mHA) that are associated with chronic graft-v-host disease (cGVHD) and disease remission. Current projects: investigate Ab anti-tumor mechanism, high-throughput serologic identification of novel mHA in the development of GVHD and prevention of disease relapse, and clinical trials of B cell therapeutics for cGVHD."},{"lastName":"Nguyen","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Dean's Office"}],"primaryAppointment":"Ph.D., Dean's Office","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=19814&type=small&showNoImage","displayName":"Khoa D Nguyen","firstName":"Khoa","href":"http://iti.stanford.edu/profiles/Khoa_Nguyen","researchInterest":"Immunology\r\nInnate Immunity\r\nMetabolism"},{"lastName":"Merker","clinicalFocus":[{"focus":"Clinical Pathology"}],"appointments":[{"appointment":"Acting Assistant Professor,Pathology"}],"primaryAppointment":"Acting Assistant Professor,Pathology","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=14772&type=small&showNoImage","displayName":"Jason Merker","firstName":"Jason","href":"http://iti.stanford.edu/profiles/Jason_Merker","researchInterest":""},{"lastName":"Fire","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Professor,Genetics"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=3989&type=small&showNoImage","displayName":"Andrew Fire","firstName":"Andrew","href":"http://iti.stanford.edu/profiles/Andrew_Fire","researchInterest":"We study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as \"self\" versus \"nonself\" or \"wanted\" versus \"unwanted\"."},{"lastName":"Roskin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=21093&type=small&showNoImage","displayName":"Krishna Roskin","firstName":"Krishna","href":"http://iti.stanford.edu/profiles/Krishna_Roskin","researchInterest":""},{"lastName":"Blish","clinicalFocus":[{"focus":"Infectious Disease"}],"appointments":[{"appointment":"Assistant Professor,Medicine - Infectious Diseases"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Assistant Professor,Medicine - Infectious Diseases","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=24377&type=small&showNoImage","displayName":"Catherine Blish","firstName":"Catherine","href":"http://iti.stanford.edu/profiles/Catherine_Blish","researchInterest":"The major goal of our research is to gain insight into the prevention and control of HIV and other viral pathogens by studying the interplay between the virus and the host immune response.  We investigate the role of various arms of the immune response, but with a particular focus on NK cells. We hope to gain additional insights into control of infectious diseases by studying how pregnancy modulates immune responses."},{"lastName":"Hwang","clinicalFocus":[],"appointments":[{"appointment":"Clinical Assistant Professor,Pediatrics - Neonatal and Developmental Medicine"}],"primaryAppointment":"Clinical Assistant Professor,Pediatrics - Neonatal and Developmental Medicine","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=4556&type=small&showNoImage","displayName":"Paul Hwang","firstName":"Paul","href":"http://iti.stanford.edu/profiles/Paul_Hwang","researchInterest":""},{"lastName":"Peltz","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=8527&type=small&showNoImage","displayName":"Gary Peltz","firstName":"Gary","href":"http://iti.stanford.edu/profiles/Gary_Peltz","researchInterest":"The laboratory develops and uses state of the art genomic methods to identify genetic factors affecting disease susceptibility, and to translate these findings into new treatments. We have developed a more efficient method for performing mouse genetic analysis, which has been used to analyze the genetic basis for 16 different biomedical traits. We are developing novel methods, and have developed a novel experimental platform that replaces mouse liver with functioning human liver tissue."},{"lastName":"Teng","clinicalFocus":[{"focus":"Cervix Cancer"},{"focus":"Cervix Cancer - Gynecologic Oncology"},{"focus":"Endometrial Cancer "},{"focus":"Endometrial Cancer - Gynecologic Oncology"},{"focus":"Fallopian Tube"},{"focus":"Fallopian Tube - Gynecologic Oncology"},{"focus":"Female & Gynecologic Cancers"},{"focus":"Germ Cell Tumors"},{"focus":"Germ Cell Tumors - Gynecologic Oncology"},{"focus":"Gestational Trophoblastic Disease"},{"focus":"Gestational Trophoblastic Disease - Gynecologic Oncology"},{"focus":"Gynecologic Cancers"},{"focus":"Gynecologic Cancers - Gynecologic Oncology"},{"focus":"Gynecologic Cancers - Medical Oncology"},{"focus":"Gynecologic Oncology"},{"focus":"Gynecology"},{"focus":"Melanoma"},{"focus":"Melanoma - Gynecologic Oncology"},{"focus":"Ovarian Cancer"},{"focus":"Ovarian Cancer - Gynecologic Oncology"},{"focus":"Urethral Cancer"},{"focus":"Urethral Cancer - Gynecologic Oncology"},{"focus":"Uterine Cancer "},{"focus":"Uterine Cancer - Gynecologic Oncology"},{"focus":"Vaginal Cancer "},{"focus":"Vaginal Cancer - Gynecologic Oncology"}],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology - Gynecologic Oncology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology - Gynecologic Oncology","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=4119&type=small&showNoImage","displayName":"Nelson Teng","firstName":"Nelson","href":"http://iti.stanford.edu/profiles/Nelson_Teng","researchInterest":"Gynecologic Malignancies\r\nImmunotherapy\r\nBiologic Response Modifiers\r\nNew Drug Development\r\nAntigenic specificities of human antibodies encoded by the VH4-34 gene"},{"lastName":"Sidow","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Genetics"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=4393&type=small&showNoImage","displayName":"Arend Sidow","firstName":"Arend","href":"http://iti.stanford.edu/profiles/Arend_Sidow","researchInterest":"We are interested in the systems biology of molecular phenotypes, and how genetic variation affects them. The lab combines experimental approaches in developing mouse embryos as well as human cancers with computational analyses. Our main data engine is high-throughput sequencing. Please refer to our web site for more information:  http://mendel.stanford.edu/SidowLab/index.html"},{"lastName":"Bustamante","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=15848&type=small&showNoImage","displayName":"Carlos Bustamante","firstName":"Carlos","href":"http://iti.stanford.edu/profiles/Carlos_Bustamante","researchInterest":"My research focuses on analyzing genome wide patterns of variation within and between species to address fundamental questions in biology, anthropology, and medicine. My group works on a variety of organisms and model systems ranging from humans and other primates to domesticated plant and animals. Much of our research is at the interface of computational biology, mathematical genetics, and evolutionary genomics."},{"lastName":"Maecker","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor (Research),Microbiology & Immunology","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=25058&type=small&showNoImage","displayName":"Holden Maecker","firstName":"Holden","href":"http://iti.stanford.edu/profiles/Holden_Maecker","researchInterest":"I'm interested in immune monitoring of T cell responses to chronic pathogens such as CMV, and the correlation of T cell response signatures with disease protection."},{"lastName":"Nadeau","clinicalFocus":[{"focus":"Allergy and Immunology"},{"focus":"Pediatric Allergy/Immun"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Immunology and Allergy"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Otolaryngology (Head and Neck Surgery)"}],"primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Immunology and Allergy","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=7485&type=small&showNoImage","displayName":"Kari Nadeau, MD, PhD","firstName":"Kari","href":"http://iti.stanford.edu/profiles/Kari_Nadeau","researchInterest":"Kari Nadeau, MD, PhD, Allergy, Immunology and Asthma\r\nOur research interests in the laboratory focus on the role of human T cells, specifically natural regulatory T cells (Treg, in immunological diseases. We aim to differentiate the mechanisms of action of regulatory T cell suppressive function. We study how pollution, such as diesel exhause, disrupt Treg suppressive function and how chemokines, like lymphotactin, enhance Treg suppressive function. We also study Treg function in tolerance."},{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://iti.stanford.edu/profiles/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Zehnder","clinicalFocus":[{"focus":"Hematology"},{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor - Med Center Line,Medicine - Hematology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=4024&type=small&showNoImage","displayName":"James L. Zehnder, M.D.","firstName":"James","href":"http://iti.stanford.edu/profiles/James_Zehnder","researchInterest":"Our laboratory focuses on translational research in 2 main areas - genomic approaches to diagnosis and minimal residual disease testing for patients with cancer, and molecular basis of disorders of thrombosis and hemostasis. My clinical focus is in diagnosis and treatment of disorders of hemostasis and thrombosis and general hematology."},{"lastName":"Arber","clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Hematopathology"},{"focus":"Pathology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=3925&type=small&showNoImage","displayName":"Daniel A. Arber, M.D.","firstName":"Daniel","href":"http://iti.stanford.edu/profiles/Daniel_Arber","researchInterest":"I study molecular genetic and immunophenotypic changes in human hematopoietic neoplasms. These include acute and chronic leukemias, lymphoma, and splenic tumors."},{"lastName":"Moreno Estrada","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Genetics"}],"primaryAppointment":"Basic Life Science Research Associate,Genetics","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=16017&type=small&showNoImage","displayName":"Andres Moreno Estrada","firstName":"Andres","href":"http://iti.stanford.edu/profiles/Andres_Moreno Estrada","researchInterest":"Human Population Genetics, Evolutionary Biology, Genomic Medicine"},{"lastName":"Henn","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=15403&type=small&showNoImage","displayName":"Brenna Henn","firstName":"Brenna","href":"http://iti.stanford.edu/profiles/Brenna_Henn","researchInterest":"Population Genetics, Human Evolution"},{"lastName":"Okada","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Neurology & Neurological Sciences"}],"primaryAppointment":"Instructor,Neurology & Neurological Sciences","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=8191&type=small&showNoImage","displayName":"Ami Okada","firstName":"Ami","href":"http://iti.stanford.edu/profiles/Ami_Okada","researchInterest":"Our interests are to understand the mechanism and control of signals that regulate proliferation and differentiation in adult tissue.  We are currently focused on studying modulation of the Hedgehog pathway in brain and muscle stem cell compartments during normal homeostasis and in degeneration or disease."},{"lastName":"Martinez","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor (Research),Surgery - Multi-Organ Transplantation","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=4474&type=small&showNoImage","displayName":"Olivia Martinez","firstName":"Olivia","href":"http://iti.stanford.edu/profiles/Olivia_Martinez","researchInterest":"EBV B cell lymphomas; pathways of immune evasion in the growth and survival of EBV B cell lymphomas;  mechanisms of graft rejection and tolerance induction; stem cell and solid organ transplantation."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://iti.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Parnes","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","imageUrl":"http://iti.stanford.edu/profiles/viewImage?facultyId=4487&type=small&showNoImage","displayName":"Jane Parnes","firstName":"Jane","href":"http://iti.stanford.edu/profiles/Jane_Parnes","researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity.  B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor.  We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance.  We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease."}]}